Highlights from January
This month’s handpicked reading list
ASTHMA
A One-Year Weight Management Program for Difficult-to-Treat Asthma With Obesity
A randomized controlled study finds that use of a dietitian-supported weight management program resulted in sustained weight loss and is a potential treatment for obesity in asthma.
RELATED VISUAL ABSTRACT »
CHEST INFECTIONS
Neutrophil-mediated Inflammatory Plasminogen Degradation, Rather Than High Plasminogen-Activator Inhibitor-1, May Underly Failures and Inefficiencies of Intrapleural Fibrinolysis
Original research suggests that inflammatory plasminogen deficiency, not high plasminogen activator inhibitor-1 activity, is a significant contributor to intrapleural fibrinolytic failure.
RELATED VISUAL ABSTRACT »
CRITICAL CARE
Incidence, Risk Factors, and Long-Term Outcomes for Extubation Failure in ICU in Patients With Obesity
Findings of a prospective, multicenter, observational study indicate that anticipation and application of preventive measures for patients with obesity before and after extubation led to similar rates of extubation failure among patients with and without obesity.
RELATED VISUAL ABSTRACT »
DIFFUSE LUNG DISEASE
Sarcoidosis and Emergency Hospitalization
Original research shows that the presence of comorbidities and the severity of respiratory failure, as reflected by oxygen requirement, are important prognostic determinants of mortality in patients with sarcoidosis.
PULMONARY AND CARDIOVASCULAR
Phosphodiesterase 5 Inhibitor Treatment Is Associated With Improved Survival in Pulmonary Hypertension Associated With COPD in the Pulmonary Vascular Research Institute GoDeep Meta-Registry
In a meta-registry, phosphodiesterase 5 inhibitor therapy was associated with a significant reduction in mortality across all tested models.
RELATED VISUAL ABSTRACT »
SLEEP
Gender Differences in Outcomes of Ambulatory and Hospitalized Patients With Obesity Hypoventilation Syndrome
Although the diagnosis of obesity hypoventilation syndrome is established at a more advanced age in women, original research finds that gender is not independently associated with worse clinical outcomes after adjusting for age.
RELATED VISUAL ABSTRACT »
RELATED PODCAST »