October 2009 Press Release
NEWS BRIEFS FROM THE October ISSUE OF CHEST
VENTILATION MASK LEAKAGE MAY CONTAMINATE HOSPITAL ROOM
exhaled air up to a distance of 1 m from patients receiving treatments. This finding raises concerns
about the potential spread of highly contagious respiratory illness within the hospital setting. Using a
patient simulator that mimicked a patient with mild lung injury, researchers from Hong Kong
measured the exhaled air leakage from two different face masks. Inspiratory pressure (IPAP) was
gradually increased while expiratory pressure remained the same. Results showed that there was
substantial exposure to exhaled air within a 1 m region of the patient receiving treatment. In addition,
results showed that higher IPAP resulted in higher contamination. Researchers suggest that health-care
workers take adequate precautions when providing NPPV support to patients with highly contagious or
unknown respiratory conditions. This study is published in the October issue of CHEST, the peerreviewed
journal of the American College of Chest Physicians.
UNCONTROLLED ASTHMA PREVALENT AMONG MINORITY CHILDREN
African-American and Hispanic children have a high incidence of uncontrolled asthma, compared with
Caucasian children with asthma. Using data from the National Asthma Survey, researchers from the
Centers for Disease Control and Prevention assessed symptom control, medication use, and health-care
utilization among 1,485 Caucasian (55 percent), African-American (20 percent) and Hispanic (25
percent) children with current asthma who reside in Alabama, California, Illinois, or Texas. The
analysis showed that, compared with Caucasian children, African-American and Hispanic children had
more indicators of poorly controlled asthma, including increased emergency health-care utilization,
more daily rescue medication use, and less use of inhaled corticosteroids. The article is published in
the October issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians.
LABAs/ICS COMBINATION THERAPY MAY DO MORE HARM THAN GOOD
Current guidelines recommend the use of inhaled corticosteroids (ICS) in combination with longacting
beta agonists (LABAs) to reduce the frequency of exacerbations in symptomatic patients with
severe to very severe chronic obstructive pulmonary disease (COPD). However, new research shows
that this combination therapy may not provide significant benefits for patients and may cause adverse
events. Researchers from Spain, Chile, and Uruguay reviewed 18 randomized controlled trials with
12,446 participants where the primary outcomes were COPD exacerbations and mortality. The analysis
showed that therapy with LABAs/ICS did not decrease severe exacerbation or all-cause or respiratory
mortality; however, moderate exacerbations were significantly reduced. Furthermore, the combination
therapy was associated with an increased risk of pneumonia. This article is published in the October
issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians.
Contact:
Jennifer Stawarz, (847) 498-8306
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