January 2009 Press Release
News Briefs From the Journal CHEST, January 2009
COMPRESSION DEVICES EFFECTIVE FOR RESTLESS LEGS SYNDROME
Pharmacotherapy for restless legs syndrome (RLS) may be ineffective or complicated by side effects.
However, new research shows that pneumatic compression devices, which apply air pressure to the leg at
regular intervals, may be an alternative therapy for RLS. Researchers from Walter Reed Army Medical
Center in Washington, DC, conducted a prospective, randomized, double-blinded trial of 35 patients with
RLS. Patients wore either a therapeutic or subtherapeutic (sham) device prior to the usual onset of RLS
symptoms for a minimum of 1 hour daily. Therapeutic compression devices significantly improved all
measured variables compared with shams, including the RLS severity score and Johns Hopkins restless legs
severity scale score. All quality of life domains also were improved, including daytime function, sleep
quality, and emotional well-being. Researchers conclude that pneumatic compression devices may be an
effective nonpharmacologic therapy for RLS. This study is published in the January issue of the journal
CHEST.
COPD ASSOCIATED WITH HIGHER DEPRESSION RATES THAN DIABETES
Chronic disease has been associated with higher rates of depression; however, new research shows that
patients with chronic obstructive pulmonary disease (COPD) are nearly two times as likely to suffer from
depression compared with patients with diabetes. Researchers from The Netherlands compared the health
characteristics of 999 patients with COPD, 978 patients with diabetes, and 2,494 healthy control subjects.
Results showed that patients with COPD were diagnosed almost twice as often with depression compared
with diabetic patients and control subjects. Furthermore, the mean time to a first diagnosis of depression was
7.7 years for patients with COPD, 5.9 years for patients with diabetes, and 7.3 years for control subjects.
Researchers speculate that the increased risk of depression is not the result of having a chronic disease in
general but specific to COPD. This study is published in the January issue of the journal CHEST.
SURVIVAL CONTINUES TO IMPROVE FOR PATIENTS WITH HIV
New research finds that the survival rate for critically ill patients with HIV continues to improve.
Researchers from the University of California, San Francisco, conducted a retrospective study of 281 adults
who were HIV-infected and admitted to the ICU during a 5-year study period, with a total of 311 admissions.
During the study period, respiratory failure remained the most common indication for ICU admissions (42
percent overall); however, the proportion of patients with respiratory failure decreased each year from 52
percent to 34 percent. Hospital survival rates also increased during the study period. Administration of
antiretroviral therapy (ART) at admission was not associated with survival, although ART was associated
with predictors that were associated with survival. This study is published in the January issue of the journal CHEST.
Contact:
Jennifer Stawarz, (847) 498-8306
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